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Stress (cortisol hormone levels)

The Adrenal Stress Profile is a powerful and precise noninvasive salivary test that evaluates bioactive levels of the body’s important stress hormones, cortisol and DHEA. This profile serves as a critical tool for uncovering biochemical imbalances underlying anxiety, depression, chronic fatigue, obesity, dysglycaemia, and a host of other clinical conditions.

This saliva test can detect imbalances in the daily circadian secretions of the stress hormones cortisol and DHEA. Imbalances in these hormones can indicate an inappropriate response that can negatively impact energy levels, emotions, and many other health complaints. These include anxiety, chronic inflammatory conditions, allergies, chronic fatigue syndrome, insomnia, depression, migraines, headaches, recurrent infections, menstrual difficulties and infertility.

The adrenal hormones cortisol and DHEA function to influence:

  • Metabolism
  • Thyroid function
  • Anti-inflammatory response
  • Resistance to stress
  • Changing the amounts of cortisol and DHEA can profoundly affect:
  • Energy levels
  • Resistance to disease
  • Emotional states
  • General sense of well-being

Although both DHEA and cortisol are produced by the adrenal cortex, they exhibit many opposing actions.

Cortisol: Many of cortisols physiological actions are geared toward the mobilisation of reserves. Cortisol is released in large amounts in response to physical, physiological, and/or psychological stress. When stressors persist, the secretion of glucocorticoids can be prolonged, leading to maladaptation of the adrenal cortex and adrenal hyperplasia.

Excess cortisol can adversely affect:

  • Bone and muscle tissue
  • Thyroid function
  • Cardiovascular function
  • Weight control
  • Sleep
  • Glucose regulation
  • Immune defense (reduced SIgA)
  • Aging
  • Over time, cortisol secretion can become impaired, resulting in an inability to respond to stress as demonstrated in conditions such as: • Chronic fatigue • Menstrual problems • Allergies • Arthritis

DHEA, in contrast to cortisol, exerts mostly anabolic actions and balances the body’s stress response.

DHEA functions to:

  • Provide substrate for the synthesis of sex hormones
  • Guard against degenerative conditions associated with ageing
  • Influence immune function and energy production
  • Affect insulin sensitivity, thyroid function, protein synthesis and others.

Imbalances of DHEA have been associated with:

  • Impaired immunity
  • Cancer
  • Depression
  • Panic disorder
  • Insulin resistance
  • Obesity
  • Alzheimers disease
  • Cardiovascular disease

This test requires the patient to take 4 saliva samples (5ml) collected at specific times over a 24-hour period (frozen)

Turnaround time: 10 days

Cost: £110 + VAT

Click here to see an Adrenal_Adrenal Function profile test report

Click here to see Sample collection procedure

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